邢 婧,水产养殖系教授,博士生导师。2003年中国海洋大学水产养殖专业毕业,获博士学位,并留校任教,2008-2009年美国纽约州立大学博士后研究。
研究方向:水产动物血细胞、淋巴细胞的分类鉴定,免疫分子及免疫细胞的应答机制,鱼类细菌性、病毒性病原的免疫原性,候选疫苗研制,鱼类疫苗效果评价等。
主持国家自然科学基金、参与973、863、国家科技支撑计划项目等国家级课题多项。发表SCI收录论文近百篇,获国家发明专利12项,作为参与人获国家技术发明二等奖1项,省部级奖5项。曾获教育部新世纪优秀人才,山东省第十一届青年科技奖,青岛市第八届青年科技奖等。兼任国家自然科学基金和重点研发计划项目评审专家、中国海洋大学民进支部主委、青岛市民进市委会委员,青岛市第十三届政协委员。
实验室链接:http://scxy.ouc.edu.cn/18836/list.htm
主持项目:
国家自然科学基金面上项目,“牙鲆疫苗免疫接种后T淋巴细胞及其亚群的效应机制研究”(32173005),2022-2025
国家自然科学基金面上项目“牙鲆CD4+ 、CD8+ T淋巴细胞亚群的鉴定及其免疫特性研究”(31672684),2017-2020年
“973”项目课题 “鱼类疫病免疫防治的系统疫苗学原理与技术途径(2012CB114406)”,子课题负责人,2012-2016年
国家科技支撑计划项目 “海洋水产病害防治生物制剂的开发与应用(2012BAD17B02)” 子课题负责人, 2012-2015年
国家重点研发计划 蓝色粮仓科技创新项目”病原诱导的适应性免疫应答的细胞与分子机制”(2018YFD0900503)子课题负责人, 2018-2022年
代表性论文:
Liu Wenjing, Xing Jing*, Tang Xiaoqian, Sheng Xiuzhen, Chi Heng, Zhan Wenbin. Characterization of co-stimulatory ligand CD80/86 and its effect as a molecular adjuvant on DNA vaccine against Vibrio anguillarum in flounder (Paralichthys olivaceus). Frontiers in Immunology, 2022, 13: 881753.
Tian Hongfei, Xing Jing*, Tang Xiaoqian, Sheng Xiuzhen, Chi Heng, Zhan Wenbin. Identification and characterization of a master transcription factor of Th1 cells, T-bet, within flounder. Frontiers in Immunology, 2021, 12: 2537.
Hongsen Xu, Jing Xing*, Xiaoqian Tang, Xiuzhen Sheng, Wenbin Zhan. The effects of CCL3, CCL4, CCL19 and CCL21 as molecular adjuvants on the immune response to VAA DNA vaccine in flounder (Paralichthys olivaceus), Developmental and Comparative Immunology. 2020,103: 103492.
Xu Hongsen, Xing Jing*, Tang Xiaoqian, Sheng Xiuzhen, Zhan Wenbin. Intramuscular administration of a DNA vaccine encoding OmpK antigen induces humoral and cellular immune responses in flounder (Paralichthys olivaceus) and improves protection against Vibrio anguillarum[J]. Fish & Shellfish Immunology, 2019, 86: 618-626.
Xing Jing, Wang Lei, Zhen Mengxiao, Tang Xiaoqian, Zhan Wenbin. Variations of T and B lymphocytes of flounder (Paralichthys olivaceus) after Hirame novirhabdovirus infection and immunization [J]. Mol Immunol, 2018, 96: 19-27.
Xing Jing, Xiao Yue’e, Tang Xiaoqian, Sheng Xiuzhen, Zhan Wenbin. Inhibition of Cyclosporine A or rapamycin on T lymphocyte counts and the influence on the immune responses of B lymphocytes in flounder (Paralichthys olivaceus)[J]. Fish Shellfish Immunol. 2017,66:78-85.
Chang Yanhong, Xing Jing*, Tang Xiaoqian, Sheng Xiuzhen, Zhan Wenbin. Haemocyanin content of shrimp (Fenneropenaeus chinensis) associated with white spot syndrome virus and Vibrio harveyi infection process[J]. Fish & shellfish immunology, 2016, 48: 185-189.
Xing Jing, Tang Xiaoqian, Ni Yongqing, Zhan Wenbin. Application of monoclonal antibody against granulocytes of scallop Chlamys farreri on granulocytes occurrence at different developmental stages and antigenic cross-reactivity of granulocytes in five other bivalve species[J]. Fish & Shellfish Immunology, 2014, 36: 315-319.
Tan Yanmiao, Xing Jing*, Zhan Wenbin. Agglutination activities of haemolymph and tissue extracts in scallop Chlamys farreri and purification of mannan-binding lectin from haemolymph[J]. Aquaculture, 2013, 400: 148-152.
Lin Tingting, Xing Jing*, Sheng Xiuzhen, Tang Xiaoqian, Zhan Wenbin. Development of a monoclonal antibody specific to granulocytes and its application for variation of granulocytes in scallop Chlamys farreri after acute viral necrobiotic virus (AVNV) infection[J]. Fish & shellfish immunology, 2011, 30(6): 1348-1353.
授权专利:
1. 邢婧,田洪飞,战文斌,等。国家发明专利. 抗牙鲆T细胞表面标志分子CD4-1的单克隆抗体及其制备方法与应用. 专利号:ZL201810284612.6;授权时间:2021.06
2. 邢婧,田洪飞,战文斌,等。国家发明专利. 抗牙鲆T细胞表面标志分子CD4-2的单克隆抗体及其制备方法与应用. 专利号:ZL201810284611.1;授权时间:2021.07
讲授本科生课程:动物免疫学,研究生课程:水产动物免疫学、鱼类疫苗研制技术
办公电话:0532-82031580;邮箱:xingjing@ouc.edu.cn