1个人简历
2009-2013,中国海洋大学海洋生命学院,学士,生物科学专业
2主要研究方向及成果
主要从事海洋无脊椎动物发育过程调控机制及环境适应分子基础研究。近年来研究成果在国际主流刊物发表SCI论文10余篇。主持承担了国家自然科学基金青年项目、国家重点研发计划项目(子任务)、山东省自然科学基金青年项目、中国博士后基金面上项目等。
3代表性文章
1. Yang, L. K., Zhang, J., Liu, D., Han, T. Y., Qin, Q. S., Wang, A. Q., Dong, B.*Ancestral glycoprotein hormone and its cognate receptor present in primitive chordate ascidian: Molecular identification and functional characterization. International Journal of Biological Macromolecules. 2023. 229: 401-412.
2. Wang, Z., Ouyang, X., Tan, Z., Yang, L. K.*, Dong, B. Quantitative phosphoproteomics reveals the requirement of DYRK1-mediated phosphorylation of ion transport- and cell junction-related proteins for notochord lumenogenesis in ascidian. Cells. 2023. 12: 921.
3. Zhang, J., Dong, B. *, & Yang, L. K.* Molecular Characterization and Expression Analysis of Putative Class C (Glutamate Family) G Protein-Coupled Receptors in Ascidian Styela clava. Biology. 2022. 11(5): 782.
4. Yang, L. K.#, Hou, Z. S.#, & Tao, Y. X.* Biased signaling in naturally occurring mutations of G protein-coupled receptors associated with diverse human diseases. Biochimica et Biophysica Acta (BBA)-Molecular Basis of Disease. 2021. 1867(1):165973.
5. Yang, L. K. & Tao, Y. X.* Alanine scanning mutagenesis of the DRYxxI motif and intracellular loop 2 of human melanocortin-4 receptor. International Journal of Molecular Sciences. 2020. 21(20):7611.