蒋志雯

蒋志雯，博士，讲师，硕士生导师

邮箱：jiangzhiwen@ouc.edu.cn

通讯地址：山东省青岛市市南区鱼山路5号

实验室网站：http://eweb.ouc.edu.cn/mls/2021/0827/c21889a345085/page.htm

承担课程：

本科生课程，生化与分子生物学实验Ⅰ

学习工作经历：

2005.09~2009.06 郑州大学生命科学学院，学士，生物技术专业

2009.09~2012.06 郑州大学生命科学学院，硕士，微生物学专业

2012.09~2015.06 中国海洋大学海洋生命学院，博士，生物化学与分子生物学专业

2015.07~2018.06 中国海洋大学海洋生命学院，博士后

2018.07至今，中国海洋大学海洋生命学院，讲师

主要科研领域：

主要从事海洋生物材料的生物活性及医学应用研究，重点开展以壳聚糖为原料的多通道神经引导管及重度烧伤敷料研究。近5年主持项目5项：国家自然科学基金青年基金、中央高校基本科研业务费—关键核心技术项目、山东省自然科学基金青年基金、中国博士后科学基金面上项目、中国海洋大学青年教师科研专项基金；获青岛市科技进步一等奖1项；以第一作者发表SCI论文10篇。

近5年代表性成果：（#共同第一；*通讯作者）

1. Zhiwen Jiang, Yijie Zhang, Yanting Wang, Shuo Wang, Jing Chang, Wanshun Liu, Baoqin Han*. Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival. Carbohydrate Polymers, 2023, 301PB, 120327(IF₂₀₂₂: 11.2).

2. Jiang Zhiwen, Li Lulu,Li Hui, Xia Lixin,Hu Huiwen, Wang Shuo,Liu Chenqi, Chi Jinhua,Yang Yan, Song Fulai, Liu Wanshun, Han Baoqin*. Preparation, biocompatibility, and wound healing effects of O-carboxymethyl chitosan nonwoven fabrics in partial-thickness burn model. Carbohydrate Polymers, 2022, 280, 119032(IF₂₀₂₂: 11.2).

3. Jiang Zhiwen, Wang Shuning, Hou Jun, Chi Jinhua, Wang Shuo, Shao Kai, Liu Wanshun, Sun Rongju, Han Baoqin*. Effects of carboxymethyl chitosan oligosaccharide on regulating immunologic function and inhibiting tumor growth. Carbohydrate Polymers, 2020, 250, 116994 (IF₂₀₂₀: 9.381).

4. Jiang Zhiwen, Song Yanan, Qiao Jing, Yang Yan, Zhang Wei, Liu Wanshun, Han Baoqin*. Rat sciatic nerve regeneration across a 10-mm defect bridged by a chitin/CM-chitosan artificial nerve graft. International Journal of Biological Macromolecules, 2019, 129: 997-1005 (IF₂₀₁₉: 5.162).

5. Jiang Zhiwen, Chi Jinhua#, Li Hui, Wang Yanting, Liu Wanshun, Han Baoqin*. Effect of chitosan oligosaccharide-conjugated selenium on improving immune function and blocking gastric cancer growth. European Journal of Pharmacology, 2021, 891, 173673 (IF₂₀₂₁: 5.195).

6. Zhiwen Jiang, Wei Zhang, Chenqi Liu, Lixin Xia, Shuo Wang, Yanting Wang, Kai Shao*, Baoqin Han*. Multichannel nerve conduit based on chitosan derivates for peripheral nerve regeneration and Schwann cell survival. Macromolecular Bioscience, 2023, 2300025 (IF₂₀₂₂: 4.6).

7. Jiang Zhiwen, Wang Yanting#, Li Lulu, Hu Huiwen, Wang Shuo, Zou Mingyu, Liu Wanshun, Han Baoqin*. Preparation, characterization and biological evaluation of transparent thin CM-chitosan/OCMC films as new wound dressings. Macromolecular Bioscience, 2022, 2100308 (IF₂₀₂₂: 4.6).  

8. Jiang Zhiwen, Li Hui, Qiao Jing,Yang Yan, Wang Yanting, Liu Wanshun, Han Baoqin*. Potential analysis and preparation of chitosan oligosaccharides as oral nutritional supplements of cancer adjuvant therapy. International Journal of Molecular Sciences, 2019, 20(4): 920 (IF₂₀₁₉: 4.556).

9. Jiang Zhiwen, Li Zhe#, Zhang Wei, Yang Yan, Han Baoqin, Liu Wanshun, Peng Yanfei*. Dietary Natural N-Acetyl-D-Glucosamine Prevents Bone Loss in Ovariectomized Rat Model of Postmenopausal Osteoporosis. Molecules, 2018, 23 (9), 2302 (IF₂₀₁₈: 3.06).

10.  Yijie Zhang, Zhiwen Jiang#, Yanting Wang, Lixin Xia, Shuqin Yu, Hongjian Li, Wei Zhang, Wanshun Liu, Kai Shao*, Baoqin Han*. Nerve regeneration effect of a composite bioactive carboxymethyl chitosan-based nerve conduit with a radial texture. Molecules, 2022, 27, 9039.  (IF₂₀₂₂: 4.6).