叶质 ，博士，副教授
邮箱：yezhi@ouc.edu.cn
承担课程：
生物技术（本科课程）、学术论文写作（研究生课程）
学习工作经历：
2006~2010，海南大学海洋学院，学士，水产养殖
2010~2012，中国海洋大学水产学院，硕士，水产养殖•免疫与病害
2012~2017，美国奥本大学，博士，水产养殖•分子遗传育种
2012~2017，美国奥本大学，博士，统计学（辅修）
2018~2021，美国华盛顿大学，博士后，发育生物学
2021至今，中国海洋大学海洋生命学院，副教授
2021至今，中国海洋大学三亚海洋研究院，副教授（双聘）
主要科研领域：
主要从事海洋动物遗传育种与发育生物学研究，主要研究方向包含：1）利用高通量组学技术，结合转基因和基因编辑技术揭示水产动物经济性状决定的遗传分子机理；2）挖掘关键基因和基因型并据此进行海洋动物定向精准分子设计育种；3）水产动物分子辅助育种和基因组选育；4）海洋动物胚胎发育的表观遗传学研究。已在国内外主流刊物发表论文30余篇，成果发表在Development、Aquaculture等国际权威期刊上。主持承担了国家自然科学基金青年基金、国家重点研发计划课题子任务、海南省科技计划三亚崖州湾科技城自然科学基金联合项目、“崖州湾”菁英人才科技专项等项目课题；入选山东省泰山学者青年专家。
代表性成果：（#共同第一；*通讯作者）
Ye, Z., Braden, C., Wills, A., and Kimelman, D. (2021). Identification of in vivo Hox13-binding sites reveals an essential locus controlling zebrafish brachyury expression. Development 148: dev199408. doi:10.1242/dev.199408. (Interviewed by Science in Seattle)
Ye, Z. and Kimelman, D. (2020). Hox13 genes are required for mesoderm formation and axis elongation during early zebrafish development. Development 147(22):dev185298. doi: 10.1242/dev.185298.. (Highlighted and interviewed by Development)
Elaswad, A., Khalil, K., Ye, Z. †, Liu, Z., Liu, S., Peatman, E., Odin, R., Vo, K., Drescher, D., Gosh, K., et al. (2018). Effects of CRISPR/Cas9 dosage on TICAM1 and RBL gene mutation rate, embryonic development, hatchability and fry survival in channel catfish. Sci Rep 8, 16499. (†：Corresponding author)
Hou, Z.#, Ye, Z.#, Zhang, D., Gao, C., Su, B., Song, L., Tan, F., Song, H., Wang, Y. and Li, C. (2017). Characterization and expression profiling of NOD-like receptor C3 (NLRC3) in mucosal tissues of turbot (Scophthalmus maximus L.) following bacterial challenge. Fish & Shellfish Immunology 66, 231–239.
Dong, X. #, Ye, Z. #, Song, L., Su, B., Zhao, H., Peatman, E. and Li, C. (2016). Expression profile analysis of two cathepsin S in channel catfish (Ictalurus punctatus) mucosal tissues following bacterial challenge. Fish Shellfish Immunol. 48, 112–118.
Guyu Qin, Zhenkui Qin, Cuiyu Lu, Zhi Ye, Ahmed Elaswad, Yulin Jin, Mohd Golam Quader Khan, Baofeng Su, Rex A Dunham (2023). Gene Editing of the Follicle-Stimulating Hormone Gene to Sterilize Channel Catfish, Ictalurus punctatus, Using a Modified Transcription Activator-like Effector Nuclease Technology with Electroporation. Biology 12 (3), 392.
Karim Khalil, Ahmed Elaswad, Hisham Abdelrahman, Maximillian Michel, Wenbiao Chen, Shikai Liu, Ramjie Odin, Zhi Ye, David Drescher, Khoi Vo, William S Bugg, Guyu Qin, Yujia Yang, Nathan JC Backenstose, Zhanjiang Liu, Roger D Cone, Rex Dunham (2023). Editing the Melanocortin-4 Receptor Gene in Channel Catfish Using the CRISPR-Cas9 System. Fishes 8 (2), 116.
Dongdong Zhang, Haitham Mohammed, Zhi Ye, Melanie A Rhodes, Wilawan Thongda, Honggang Zhao, Lauren N Jescovitch, S Adam Fuller, D Allen Davis, Eric Peatman (2022). Transcriptomic profiles of Florida pompano (Trachinotus carolinus) gill following infection by the ectoparasite Amyloodinium ocellatum. Fish & Shellfish Immunology 125, 171-179.
Guyu Qin, Zhenkui Qin, Cuiyu Lu, Zhi Ye, Ahmed Elaswad, Max Bangs, Hanbo Li, Yiliu Zhang, Yingqi Huang, Huitong Shi, Kamal Gosh, Nermeen Y Abass, Khoi Vo, Ramjie Odin, William S Bugg, Nathan JC Backenstose, David Drescher, Zachary Taylor, Timothy Braden, Baofeng Su, Rex A Dunham (2022). Gene Editing of the Catfish Gonadotropin-Releasing Hormone Gene and Hormone Therapy to Control the Reproduction in Channel Catfish, Ictalurus punctatus. Biology 11 (5), 649.
Nermeen Y Abass, Zhi Ye, Ahmed Alsaqufi, Rex A Dunham (2022). Comparison of growth performance among channel-blue hybrid catfish, ccGH transgenic channel catfish, and channel catfish in a tank culture system. Scientific Reports 12 (1), 740.
