王岩,博士,教授,博士生导师
电话:0532-82031517
学习工作经历:
2003.09-2007.06,山东师范大学生命科学学院,本科
2007.09-2012.12,山东大学微生物技术国家重点实验室,博士
2010.10-2012.10,美国内布拉斯加-林肯大学化学系访问学者
2013.02-2014.05,美国内布拉斯加-林肯大学化学系博士后
2014:05-2019.07,中国海洋大学海洋生命学院,“青年英才第三层次”,副教授,硕士生导师
2019.7-至今,中国海洋大学海洋生命学院,“青年英才第一层次”,教授,博士生导师
主要科研领域:
主要从事海洋微生物学与海洋生物技术研究,近年来主要研究方向为:(1)海洋微生物化学信号通讯与互作;(2)海洋微生物环境适应与生态效应;(3)海洋微生物应用技术;(4)海洋微生物与抗菌新资源的机制与发掘利用。研究成果主要发表在The ISME Journal,Trends in Microbiology,Journal of Medicinal Chemistry,mBio,PLOS Genetics等国际权威期刊。主持国家自然科学基金面上项目(4项),2024年山东省自然科学基金杰出青年基金,2021年入选山东省泰山学者青年专家,2016年入选中国科协“青年人才托举工程”,2021年获山东省海洋与渔业青年科技奖,2020年获第十二届青岛市青年科技奖。
代表性成果:(*通讯作者)
Zhu Y#, Han Y#, Liu G#, Bian Z, Yan X, Li Y, Long H, Yu G, Wang Y*. 2022. Novel indole-mediated potassium ion import system confers a survival advantage to the Xanthomonadaceae family. The ISME Journal, 16(7), 1717–1729. https://doi.org/10.1038/s41396-022-01219-6.
Zhu Y#, Dou Q#, Du L, Wang Y*. 2023. QseB/QseC: a two-component system globally regulating bacterial behaviors. Trends in Microbiology, 31(7), 749–762. https://doi.org/10.1016/j.tim.2023.02.001.
Yu R*, Wang J, So L, Peta J. Harvey, Shi J, Liang J, Dou Q, Li X, Yan X, Huang Y, Xu Q, Kaas Q, Chow H, Wong K, Craik D, Zhang X, Jiang T, Wang Y*. 2020. Enhanced activity against multi-drug resistant bacteria through coapplication of an analogue of Tachyplesin I and an inhibitor of the QseC/B signaling pathway. Journal of Medicinal Chemistry, 63(7), 3475–3484. https://doi.org/10.1021/acs.jmedchem.9b01563.
Wang Y*#, Tian T#, Zhang J#, Jin X#, Yue H, Zhang X, Du L, Bai F*. 2019. Indole reverses intrinsic antibiotic resistance by activating a novel dual-function importer. mBio, 10(3), e00676-19. https://doi.org/10.1128/mBio.00676-19.
Cao Q, Ge C, Wang X, Harvey P. J, Zhang Z, Ma Y, Wang X, Jia X, Mobli M, Craik D. J, Jiang T, Yang J, Wei Z, Wang Y*, Chang S*, Yu R*. 2023. Designing antimicrobial peptides using deep learning and molecular dynamic simulations. Briefings in Bioinformatics, 24(2), bbad058. https://doi.org/10.1093/bib/bbad058
Zhong J#, Yan, X#, Zuo X#, Zhao X#, Yang J, Dou Q, Peng L, Zhu Y, Xiao Y, Bian Z, He D, Xu Q, Wright S, Li Y, Du L, Wang Y*, Yuan J*. 2022. Developing a new treatment for superficial fungal infection using antifungal collagen-HSAF dressing. Bioengineering & Translational Medicine, 7(3), e10304. https://doi.org/10.1002/btm2.10304.
Zhang R, Wang Y*. 2023. EvgS/EvgA, the unorthodox two-component system regulating bacterial multiple resistance. Applied and Environmental Microbiology, 89(12), e0157723. https://doi.org/10.1128/aem.01577-23.
Feng T#, Han Y#, Li B#, Li Z#, Yu Y, Sun Q, Li X, Du L, Zhang X, Wang Y*. 2019. Interspecies and intraspecies signals synergistically regulate Lysobacter enzymogenes twitching motility. Applied and Environmental Microbiology, 85(23), e01742-19. https://doi.org/10.1128/AEM.01742-19.
Han Y#, Wang Y#, Yu Y, Chen H, Shen Y*, Du L*. 2017. Indole-induced reversion of intrinsic multi-antibiotic resistance in Lysobacter enzymogenes. Applied and Environmental Microbiology, 83(17), e00995-17. https://doi.org/10.1128/AEM.00995-17.
Li Y, Feng T, Wang Y*. 2022. The role of bacterial signaling networks in antibiotics response and resistance regulation. Marine Life Science & Technology, 4(2), 163–178. https://doi.org/10.1007/s42995-022-00126-1.