隗健凯,博士,副教授
邮箱:weijiankai@ouc.edu.cn
电话:0532-85906579
实验室网站:http://iemb.ouc.edu.cn/18975/list.htm
承担课程:
系统生物学
科学素养-进程与实践
学习工作经历:
2006~2010,厦门大学海洋与环境学院,学士,海洋科学专业
2010~2015,中国科学院海洋研究所,博士,海洋生物学专业
2015~2018,中国海洋大学海洋生命学院,博士后
2015~2022,中国海洋大学海洋生命学院,讲师
2023至今,中国海洋大学海洋生命学院,副教授
主要科研领域:
自然界中动物的形态和发育过程展现出广泛的多样性,理解这种多样性的起源和演化是进化发育生物学领域的核心问题之一。本人主要利用海鞘作为模式生物,针对其早期发育的转录调控、器官发生与演化、形态特征的适应性进化等方面开展工作。已在国内外主流刊物发表论文三十余篇,主持承担了国家自然科学基金青年基金、国家自然科学基金面上项目,山东省优秀中青年科学家奖励基金,崂山实验室蓝色生命前沿探索项目,中国博士后科学基金面上项目等项目课题。
代表性成果:(#共同第一;*通讯作者)
Wei, J.#, Liu, P.#, Liu, F.#, Jiang, A., Qiao, J., Pu, Z., Wang, B., Zhang, J., Jia, D., Li, Y.*, Wang, S.* and Dong, B.* (2023) EDomics: a comprehensive and comparative multi-omics database for animal evo-devo. Nucleic Acids Research, 51, D913-D23.
Jiang, A.#, Han, K.#, Wei, J.#, Su, X.#, Wang, R., Zhang, W., Liu, X., Qiao, J., Liu, P., Liu, Q., Zhang, J., Zhang, N., Ge, Y., Zhuang, Y., Yu, H., Wang, S., Chen, K., Xu, X., Yang, H., Fan, G.* and Dong, B.* (2023) Spatially-resolved single-cell atlas of ascidian endostyle provides insights into the origin of vertebrate pharyngeal organs. bioRxiv 2023.05.03.539335.
Wei, J.#, Zhang, W.#, Leng, L.#, Jiang, A.#, Li, Y., Ge, Y., Zhang, Q., Zhang, L., Yu, H., Chen, K.* and Dong, B.* (2022) Spatiotemporal dynamics of zygotic genome activation in basal chordates revealed by interspecific hybrids. bioRxiv 2022.2006.2001.494324.
Zhang, J.#, Wei, J.#, Yu, H.* and Dong, B*. (2021) Genome-Wide Identification, Comparison, and Expression Analysis of Transcription Factors in Ascidian Styela clava. International Journal of Molecular Sciences, 22, 4317.
Wei, J., Zhang, J., Lu, Q., Ren, P., Guo, X., Wang, J., Li, X., Chang, Y., Duan, S., Wang, S., Yu, H., Zhang, X., Yang, X., Gao, H. and Dong, B.* (2020) Genomic basis of environmental adaptation in the leathery sea squirt (Styela clava). Molecular Ecology Resources, 20, 1414-1431. (highlight paper)
Wei, J., Gao, H., Yang, Y., Liu, H., Yu, H., Chen, Z.* and Dong, B.* (2020) Seasonal dynamics and starvation impact on the gut microbiome of urochordate ascidian Halocynthia roretzi. Animal Microbiome, 2, 30.
Wang, J.#, Zhang, L.#, Lian, S.#, Qin, Z.#, Zhu, X.#, Dai, X., Huang, Z., Ke, C., Zhou, Z., Wei, J., Liu, P., Hu, N., Zeng, Q., Dong, B., Dong, Y., Kong, D., Zhang, Z., Liu, S., Xia, Y., Li, Y., Zhao, L., Xing, Q., Huang, X., Hu, X., Bao, Z., Wang, S.* (2020) Evolutionary transcriptomics of metazoan biphasic life cycle supports a single intercalation origin of metazoan larvae. Nature Ecology & Evolution, 4, 725-736.
Wei, J. and Dong, B.* (2018) Identification and expression analysis of long noncoding RNAs in embryogenesis and larval metamorphosis of Ciona savignyi. Marine Genomics, 40, 64-72.
Wei, J., Wang, G., Li, X., Ren, P., Yu, H. and Dong, B.* (2017) Architectural delineation and molecular identification of extracellular matrix in ascidian embryos and larvae. Biology Open, 6, 1383-1390. (cover paper)
Wei, J., Zhang, X., Yu, Y., Huang, H., Li, F. and Xiang, J.* (2014) Comparative transcriptomic characterization of the early development in Pacific white shrimp Litopenaeus vannamei. PLoS One, 9, e106201. (cited > 100)