汲广东 ,博士,副教授
邮箱:jamesdong@ouc.edu.cn
电话:0532-82031665
承担课程:
承担本科《免疫学》授课,参与《免疫与病毒》、《健康管理与免疫》等本科课程的讲授,参与研究生《海洋动物免疫》等课程的讲授。
学习工作经历:
1995~1999,华中农业大学水产学院,学士,名特水产养殖专业
1999~2002,华中农业大学水产学院,学士,硕士,鱼类遗传育种
2002~2006,中国科学院水生生物研究所,博士
2006至今,中国海洋大学海洋生命学院,讲师,副教授
主要科研领域:
主要从事文昌鱼和鱼类发育比较免疫与进化研究。本团队近年来致力于从进化角度探索经典的先天性免疫分子功能的保守性,同时从遗传和发育的角度研究这些免疫分子在鱼类早期发育中扮演的角色,探索它们的功能在胚胎与成体中的差异。已在国内外主流刊物发表论文上20余篇,成果发表在Dev Comp Immunol、Front Immunol等国际期刊上。主持承担了国家自然科学基金(面上)以及山东省自然科学基金等项目。
代表性成果:(#共同第一;*通讯作者)
Duan H, Yang S, Zhang X, Ji G*. 2022. Bacterial-agglutinating and opsonic activities of RIPK1 in zebrafish. Comp Biochem Physiol C Toxicol Pharmacol 261:109443.
Li X, Guo R, Yang S, Zhang X, Yin X, Teng L, Zhang S, Ji G*, Li H*. 2022. Cd248a and Cd248b in zebrafish participate in innate immune responses. Front Immunol 13:970626.
Yang S, Zhang X, Li X, Yin X, Teng L, Ji G*, Li H*. 2022. Evolutionary and Expression Analysis of MOV10 and MOV10L1 Reveals Their Origin, Duplication and Divergence. Int J Mol Sci 23.
Chen Y, Yao L, Wang Y, Ji X, Gao Z, Zhang S, Ji G*. 2021. Identification of ribosomal protein L30 as an uncharacterized antimicrobial protein. Dev Comp Immunol 120:104067.
Li C, Zhong S, Ni S, Liu Z, Zhang S*, Ji G*. 2021. Zebrafish Ism1 is a novel antiviral factor that positively regulates antiviral immune responses. Dev Comp Immunol 125:104210.
Yuan J, Feng Y, Zhang X, Jl G*. 2021. 哺乳动物类白蛋白家族的结构、功能与演化. 海洋科学 45:89-97.
Jiang C, Wang P, Liu S, Wang Y, Li J, Ji G*. 2019. Administration of Yeast Glucan on Immunity of Offspring in Turbot Scophthalmus maximus: A Trans-Generational Immune-Enhancing Effect. Journal of Ocean University of China 18:997-1003.
Bai Y, Liu S, Wang X, Du X, Ji G*, Zhang S*. 2017. Identification of neuroglobin as a novel player in anti-bacterial responses in amphioxus. Dev Comp Immunol 77:157-165.
Gao Z, Qu B, Ma Z, Jiao D, Ji G*, Zhang S*. 2017. Identification and functional characterization of a novel member of low-density lipoprotein receptor-related protein (LRP)-like family in amphioxus. Gene 618:42-48.
Liu X, Cao X, Wang S, Ji G*, Zhang S, Li H*. 2017. Identification of Ly2 members as antimicrobial peptides from zebrafish Danio rerio. Bioscience Reports 37.
Wu B, Liu Z, Zhou L, Ji G*, Yang A*. 2015. Molecular cloning, expression, purification and characterization of vitellogenin in scallop Patinopecten yessoensis with special emphasis on its antibacterial activity. Dev Comp Immunol 49:249-258.
Xu Z#, Ji G#, Shen J, Wang X, Zhou J, Li L*. 2012. SOX9 and myocardin counteract each other in regulating vascular smooth muscle cell differentiation. Biochem Biophys Res Commun 422:285-290.