张霞

张霞

职称：

副教授

办公电话：

0532-66781922

个人邮箱：

zxcindy@ouc.edu.cn

研究领域或方向：

（1）金属配合物的合成及生物活性研究

（2）芳香多羧酸聚合物的合成及性质研究

教育与研究经历：

2009－至今中国海洋大学化学化工学院讲师

2007－2008，韦恩州立大学药理学专业， 联合培养博士

2005－2009，中国海洋大学海洋化学工程与技术专业，获博士学位

2002－2005，济南大学应用化学专业，获硕士学位

1998－2002，济南大学环境工程专业，获学士学位

学术成果：

1. Guimei Huang,Xia Zhang*,  Yuhua Fan,  Caifeng Bi, Xingchen Yan, Zhongyu Zhang, andNan Zhang Synthesis, Crystal Structure and Theoretical Calculation of a NovelNickel(II) omplex with Dibromotyrosine and 1,10-Phenanthroline, Bull KoreanChemistry Society, 34(10): 2889-2894, 2013. (SCI)

2. Nan Zhang,Yu-Hua Fan,Cai-Feng Bi,Xia Zhang,Peng-Fei Zhang,Zhong-Yu Zhang,Xin LiSynthesis, Crystal Structure, Fluorescence and Thermostability of Ni(II),Zn(II), Cd(II) omplexes with Schiff Base 2-Acetylpyridine-d-tryptophan. Journal of Inorganic andOrganometallic  Polymers and Materials,23(6): 1492-1500,2013. (SCI)

3. Zhang  Zhen, Bi Caifeng, Buac Daniela, Fan Yuhua,Zhang Xia, Zuo Jian, Zhang Pengfei,Zhang Nan, Dong Lili, Dou Q. Ping*,Organic cadmium complexesas proteasome inhibitors and apoptosis inducersinhuman breast cancer cells .Journal of Inorganic Biochemistry , 123:1-10,2013（SCIIF 3.2）

4.Zhang Xia, Frezza Michael, MilacicVesna, Ronconi Luca, Fan Yuhua, Bi Caifeng and Dou Q.Ping*. Inhibition oftumor proteasome activity by gold dithiocarbormate complexes via bothredox-dependent and independent processes. Journal of Cellular Biochemistry.109: 162-172, 2010.（SCIIF 3.0）

5. Xiao Yan, Chen Di, Zhang Xia,Cui Qiuzhi, FanYuhua, Bi Caifeng, Dou Q. Ping*.Molecular study on copper-mediated tumor proteasome inhibition and celldeath. International Journal of Oncology, 37(1): 81-87, 2010. (SCI)

6. Fan Yuhua*, WangYufang, BiCaifeng, Wang Qiang, Zhang Xia.Synthesis, crystal structure, and fluorescence properties of a Two-DimensionalCopper (Ⅱ) complex with Schiff base. Russian Journal of Coordination Chemistry.36(7): 509-513, 2010.  (SCI)

7. Xia Zhang, Caifeng Bi, Yuhua Fan, CindyCui, Di Chen and Q. Pingdou. Induction of tumor cell apoptosis by taurineschiff base copper complex is associated with inhibition of the proteasomalactivity.International Journal of Molecular Medicine, 22: 677-682 , 2008.(SCI )

8. Yan Xiao, Caifeng Bi, Yuhua Fan,Cindy Cui, Xia Zhang and Q. PingDou. L-glutamine Schiff base coppercomplex as a proteasome inhibitor and an apoptosis inducer in human cancercells. International Journal of Oncology, 33: 1073-1079,2008. (SCI)